fortebio(ForteBio Streamlining Biologics Development)
Introduction
Biotherapeutic drugs, or biologics, are becoming increasingly important in treating several diseases. However, their large size and complex structures make their development and production a challenging task. ForteBio is a leading biotechnology company that provides advanced analytical tools and solutions to accelerate the development of biologic drugs. This article will explore the capabilities of ForteBio and how it streamlines biologics development.
Background of ForteBio
ForteBio was founded in the year 2000 and was later acquired by Pall Corporation. It has its headquarters in California, United States, and several branch offices worldwide. ForteBio provides high-end analytical tools and solutions that are designed to work with different biomolecules. Its products are designed to provide accurate and sensitive results in real-time, thus reducing the time taken for drug development significantly.
ForteBio’s Analytical Tools
ForteBio provides several analytical tools that are used in biologics development. One such tool is the Octet system, which uses a BioLayer Interferometry (BLI) technology to detect and quantify binding between biomolecules. The Octet system has several advantages over traditional methods, including its ability to work with small sample volumes, label-free analysis, and real-time measurement of binding kinetics. The Octet system has been used by many researchers in the development of biosimilars and other biologics.
ForteBio’s Solutions for Screening and Characterization
ForteBio provides several solutions that aid in screening and characterization of biomolecules. Its flagship product, the BLItz system, is an entry-level system that provides quick and accurate results in real-time. It is designed to work with a wide range of sample types and can perform label-free assays. The BLItz system is ideal for small-scale production and proof-of-concept studies. ForteBio also provides other solutions, including the Protein A and G Kits that help in affinity purification of antibodies and biologics.
ForteBio’s Solutions for Protein Quantification and Stability Analysis
ForteBio provides solutions for protein quantification and stability analysis. Its ProQuantum system is designed to quantify protein concentration in real-time, without the need for extensive purification or labeling. The ProQuantum system is highly accurate and sensitive and can detect low concentrations of proteins. ForteBio’s Ambr system, on the other hand, is used for stability monitoring and formulation development of biologics. It can evaluate the impact of different storage conditions on the stability of biologics and generate data that aid in formulation development.
ForteBio’s Impact on Biologics Development
ForteBio’s analytical tools and solutions h*e significantly impacted the biologics development process. By providing accurate and sensitive results in real-time, researchers can reduce the time taken for drug development significantly. ForteBio’s solutions also aid in reducing costs associated with biologics development by eliminating the need for extensive purification and labeling steps. It has become an indispensable tool for researchers developing biosimilar and other biologics, and its impact on biologics development is expected to grow in the future.
In conclusion, ForteBio’s advanced analytical tools and solutions h*e become essential in the development of biologics. Its technologies allow researchers to get accurate and real-time data, reducing the time and costs associated with developing and manufacturing biologics. With the growing demand for biologics, ForteBio’s contribution to the drug development industry is significant.
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