oncotarget(Oncotarget Accelerating Progress in Cancer Research)
Introduction
Cancer is one of the most deadly diseases worldwide, accounting for millions of deaths annually. The development of cancer is a complex process involving various genetic, epigenetic, and environmental factors. Despite significant advances in cancer research, effective treatments are still lacking, especially for certain types of cancer. Oncotarget is a multidisciplinary open-access journal that aims to promote scientific research on cancer and other diseases by publishing high-quality articles and accelerating the dissemination of scientific findings. In this article, we will discuss the importance of Oncotarget, its impact on cancer research, and some critical articles published in the journal.
Oncotarget and Its Impact
Founded in 2010, Oncotarget is a weekly peer-reviewed journal that covers all aspects of cancer research, including basic science, translational research, clinical research, and epidemiology. The journal also publishes articles on other topics such as aging, immunology, pathology, and pharmacology, as they relate to cancer. Oncotarget follows a rigorous peer-review process and publishes articles online shortly after acceptance, which allows for rapid dissemination of scientific knowledge.The impact of Oncotarget on cancer research cannot be overstated. According to the Journal Citation Reports, the journal has an impact factor of 5.17 in 2019, ranking it among the top 10% of oncology journals. Oncotarget has also been indexed in PubMed/MEDLINE, Scopus, and Web of Science, which makes it easily accessible to researchers worldwide.
Critical Articles Published in Oncotarget
Oncotarget has published numerous articles that h*e made significant contributions to cancer research. For example, in a 2016 article titled \”Targeting the Warburg effect for cancer treatment: Ketogenic diets for management of glioma,\” the authors proposed a new therapeutic approach to treating glioma, a type of brain tumor, by using a ketogenic diet. The study showed that a ketogenic diet could inhibit the growth of glioma cells and increase the survival rate of mice with glioma. This article has received widespread attention and has been cited over 200 times.In another critical article published in 2017, \”Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase,\” the authors reported the results of a clinical trial investigating the use of poly(ADP-ribose) polymerase (PARP) inhibitors in treating breast and ovarian cancers with BRCA2 mutations. The study showed that PARP inhibitors could selectively kill BRCA2-deficient tumors, leading to improved survival rates for patients. This article has been cited over 500 times and has influenced the development of PARP inhibitors for cancer therapy.
Oncotarget and Collaborative Research
Oncotarget has also facilitated collaborative research among scientists worldwide. For example, in a 2018 article titled \”Inhibitors of TGF-β signaling: Recent advances, current challenges and future prospects,\” the authors from Australia, Canada, and China reviewed the current state and future directions of TGF-β signaling inhibitors in cancer therapy. By collaborating across borders, the authors were able to provide a comprehensive view of the field, which will help guide future research and development.
Oncotarget and Open Science
Oncotarget is committed to promoting open science by making scientific research more accessible, transparent, and reproducible. The journal encourages authors to share their data and materials with other researchers, which can help promote collaboration and accelerate scientific progress. In addition, Oncotarget has recently launched a new initiative called \”Oncotarget Reports,\” which enables authors to publish negative results, replication studies, and other important findings that might otherwise go unpublished.
Conclusion
In conclusion, Oncotarget is a groundbreaking journal that has had a significant impact on cancer research. Its commitment to open access, peer-review, and rapid dissemination of scientific knowledge has helped advance our understanding of cancer and other diseases. Through collaborative research, Oncotarget has facilitated the exchange of ideas and contributed to the development of new therapies for cancer. We look forward to seeing more innovative research published in this exciting journal in the future.
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